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Founding Senior Frontend Engineer

Rayni

Rayni

Software Engineering
United States
Posted on Jan 22, 2026
Learn about our team, benefits, culture, and values here: Rayni Careers
TLDR

Shape the entire UI/UX of our products - from Design to Implementation - with independence and ownership - Your ideas matter!

Go from idea →

  • designing/prototyping with AI →
  • Production-ready frontend (TypeScript, React, and Next.js) →
  • Integrate with Backend →
  • Deploy
You will…
  1. Own the core of the product and get opportunities to work with customers (scientists, some of whom are literally solving brain cancer)
  2. Work with an incredibly accomplished, mature, and most importantly, a kind set of teammates.
  3. Be compensated well with meaningful founding-level equity
Who We Seek

Sr. Frontend Engineer with Experience Building 0→1

  • 3+ years of experience in building & managing frontend services deployed to production.
  • Experience with building B2B/enterprise software
  • Experience with building and integrating REST APIs
  • 2+ years of experience in modern web design
  • A portfolio showing UI design + production code (screens, prototypes, Github, pattern library)
  • You take complete ownership of the work you ship.
Must have Experience
  • TypeScript, React, and Next.js
  • Some experience with reading and understanding Python (or another OOP language)
  • Using Cursor, Claude Code, Codex, etc.
Nice to Have
  • Experience with building Generative AI applications
  • Previous 0→1 experience, or early-stage startup experience, or other evidence of scrappiness
  • Exposure to Scientific Instruments / Biotech or adjacent Research
Medium/Long-Term Responsibilities
  • Contribute to building the product engineering team, lead and mentor new engineers
  • Scale the product to millions of users
Location

📍 San Mateo, CA or Remote

Work Authorization / Sponsorship

Applicants must be authorized to work in the U.S. without employer sponsorship. Rayni is not able to sponsor or transfer work visas for this position.

About Rayni

At Rayni (www.rayni.ai), our goal is to accelerate the pace of discovery across Biotechs and Pharma. We are starting with helping scientists operate their instruments with complete confidence, with personalized guidance.

Funding

We have raised over $1.8M in funding from top investors, angels, and winning the world's largest academic accelerator program (New Venture Challenge at the University of Chicago).

More media from the University of Chicago’s Polsky Center for Entrepreneurship.